Impact of epidural analgesia on survival in patients undergoing complete cytoreductive surgery for ovarian cancer.
نویسندگان
چکیده
BACKGROUND Potential benefits of regional analgesia in reduction of cancer recurrence have been reported for breast and prostate cancer. The aim of this study was to evaluate the influence of regional analgesia on recurrence-free survival and overall survival in patients with advanced-stage ovarian cancer (ASOC) following complete cytoreduction. PATIENTS AND METHODS This is a retrospective study of 104 patients who had undergone complete cytoreduction for ASOC between 01/2007 and 12/2009: 51 with patient controlled epidural analgesia (PCEA) and 53 without PCEA. RESULTS No significant difference was found between the two groups in terms of overall survival, while there was a trend in favour of PCEA for disease free survival. CONCLUSION In our study, regional analgesia had no clear impact on cancer recurrence. More studies on this subject are warranted in order to determine the possible impact of regional analgesia on ASOC.
منابع مشابه
مرکزیت دادن جراحی سرطان تخمدان آیا به نفع بیماران است؟
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OBJECTIVE Many studies have compared different methods of postoperative pain management in abdominal laparotomy patients; however, the conclusions have been inconsistent and controversial. This study aimed to compare the pain scores and complications of patients who underwent cytoreductive surgery for ovarian cancer and used either patient-controlled epidural analgesia (PCEA) or patient-control...
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As the overall prognosis for patients with ovarian cancer is poor, the management of this condition should be restricted to expert multi-disciplinary teams in gynaecological oncology. Apparent early stage ovarian cancer requires accurate and complete staging so that potential sites for metastases are not missed. Omitting adequate staging may have significant consequences including a negative im...
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عنوان ژورنال:
- Anticancer research
دوره 32 4 شماره
صفحات -
تاریخ انتشار 2012